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[urri]

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Cc1nncn1C
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[mishka]

из 3,4-dimethyl-1,2,4-triazole-5-thione

Stage #1: 4,5-dimethyl-2,4-dihydro-3H-1,2,4-triazole-3-thione, With dihydrogen peroxide; acetic acid In dichloromethane; water at 0 - 20℃;
Stage #2: With sodium hydroxide In water pH=12;

Experimental Procedure
73%
Current Patent Assignee: MEDIVATION TECHNOLOGIES - US2010/35883, 2010, A1
Location in patent: Page/Page column 81


With dihydrogen peroxide; acetic acid In dichloromethane at 0 - 20℃;

Experimental Procedure
Current Patent Assignee: BIOMARIN PHARMACEUTICAL - WO2011/130661, 2011, A1
Location in patent: Page/Page column 155
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из 3,4-Dimethyl-5-mercapto-1,2,4-triazol

With dihydrogen peroxide; acetic acid In dichloromethane at 20℃; for 3h;
81%
Ivanova, Natalia V.; Sviridov, Sergey I.; Shorshnev, Sergey V.; Stepanov, Aleksander E.
[Synthesis, 2006, # 1, art. no. T05405SS, p. 156 - 160]
---------
aus 3,4-Dimethyltriazolon-5 und LiAlH4 in THF;


Daunis et al.
[Bulletin de la Societe Chimique de France, 1971, p. 3296,3297-3299]

[urri]

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